Hidden Copying Software

Hi list,

A friend of mine who is a medical professor asked me if
it is possible to copy his usb thumb drive from their
class room pc without knowing it? he told me maybe
there's a hidden software that copying it in the background?

His exam from his usb thumbdrive was exposed all over
to his student.I told him that you need a very high tech
software or expensive to do it? Is any such software capable
of this? this some kind of impossible task in my views.

Thanks.

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